Screening of immune-related secretory proteins linking chronic kidney disease with calcific aortic valve disease based on comprehensive bioinformatics analysis and machine learning

Screening of immune-related secretory proteins linking chronic kidney disease with calcific aortic valve disease based on comprehensive bioinformatics analysis and machine learning

Abstract Background Chronic kidney disease (CKD) is one of the most significant cardiovascular risk factors, playing vital roles in various cardiovascular diseases such as calcific aortic valve disease (CAVD). We aim to explore the CKD-associated genes potentially involving CAVD pathogenesis, and to...

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Bibliographic Details
Main Authors: Enyi Zhu, Xiaorong Shu, Zi Xu, Yanren Peng, Yunxiu Xiang, Yu Liu, Hui Guan, Ming Zhong, Jinhong Li, Li-Zhen Zhang, Ruqiong Nie, Zhihua Zheng
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Journal of Translational Medicine
Subjects:
Chronic kidney disease
Calcific aortic valve disease
Immune cell infiltration
Diagnostic value
Secretory proteins
Online Access:https://doi.org/10.1186/s12967-023-04171-x

Internet

https://doi.org/10.1186/s12967-023-04171-x

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