mTOR-Controlled Autophagy Requires Intracellular Ca(2+) Signaling.

mTOR-Controlled Autophagy Requires Intracellular Ca(2+) Signaling.

Autophagy is a lysosomal degradation pathway important for cellular homeostasis and survival. Inhibition of the mammalian target of rapamycin (mTOR) is the best known trigger for autophagy stimulation. In addition, intracellular Ca(2+) regulates autophagy, but its exact role remains ambiguous. Here,...

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Bibliographic Details
Main Authors: Jean-Paul Decuypere, Dimphny Kindt, Tomas Luyten, Kirsten Welkenhuyzen, Ludwig Missiaen, Humbert De Smedt, Geert Bultynck, Jan B Parys
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3614970?pdf=render

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http://europepmc.org/articles/PMC3614970?pdf=render

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