Functional characterization of an Aspergillus fumigatus calcium transporter (PmcA) that is essential for fungal infection.

Aspergillus fumigatus is a primary and opportunistic pathogen, as well as a major allergen, of mammals. The Ca(+2)-calcineurin pathway affects virulence, morphogenesis and antifungal drug action in A. fumigatus. Here, we investigated three components of the A. fumigatus Ca(+2)-calcineurin pathway, p...

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Main Authors: Taísa Magnani Dinamarco, Fernanda Zanolli Freitas, Ricardo S Almeida, Neil Andrew Brown, Thaila Fernanda dos Reis, Leandra Naira Zambelli Ramalho, Marcela Savoldi, Maria Helena S Goldman, Maria Célia Bertolini, Gustavo Henrique Goldman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3359301?pdf=render