Mechanistic Studies on the Absorption-Enhancing Effects of Gemini Surfactant on the Intestinal Absorption of Poorly Absorbed Hydrophilic Drugs in Rats

Mechanistic Studies on the Absorption-Enhancing Effects of Gemini Surfactant on the Intestinal Absorption of Poorly Absorbed Hydrophilic Drugs in Rats

Generally, the use of absorption enhancers might be the most effective approaches to ameliorate the enteric absorption of poorly absorbed substances. Among numerous absorption enhancers, we already reported that a gemini surfactant, sodium dilauramidoglutamide lysine (SLG-30) with two hydrophobic an...

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Bibliographic Details
Main Authors: Tammam Alama, Kosuke Kusamori, Masaki Morishita, Hidemasa Katsumi, Toshiyasu Sakane, Akira Yamamoto
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Pharmaceutics
Subjects:
absorption enhancer
gemini surfactant
intestinal absorption
poorly absorbed drug
Caco-2 cells
Online Access:https://www.mdpi.com/1999-4923/11/4/170

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https://www.mdpi.com/1999-4923/11/4/170

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