A Targeted Gene Panel for Circulating Tumor DNA Sequencing in Neuroblastoma

A Targeted Gene Panel for Circulating Tumor DNA Sequencing in Neuroblastoma

BackgroundLiquid biopsies do not reflect the complete mutation profile of the tumor but have the potential to identify actionable mutations when tumor biopsies are not available as well as variants with low allele frequency. Most retrospective studies conducted in small cohorts of pediatric cancers...

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Bibliographic Details
Main Authors: Flora Cimmino, Vito Alessandro Lasorsa, Simona Vetrella, Achille Iolascon, Mario Capasso
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Oncology
Subjects:
genetic mutation
bioinformactics analysis
next generation sequencing
neuroblastoma
liquid biopsy and circulating tumor DNA
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.596191/full

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https://www.frontiersin.org/articles/10.3389/fonc.2020.596191/full

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