The landscape of mitophagy in sepsis reveals PHB1 as an NLRP3 inflammasome inhibitor

Mitophagy is a selective autophagy targeting damaged and potential cytotoxic mitochondria, which can effectively prevent excessive cytotoxic production from damaged mitochondria and alleviate the inflammatory response. However, the potential role of mitophagy in sepsis remains poorly explored. Here,...

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Bibliographic Details
Main Authors: Shipeng Chen, Jinqi Ma, Ping Yin, Fang Liang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1188482/full