Maternal Separation Alters Ethanol Drinking and Reversal Learning Processes in Adolescent Rats: The Impact of Sex and Glycine Transporter Type 1 (GlyT1) Inhibitor

Maternal Separation Alters Ethanol Drinking and Reversal Learning Processes in Adolescent Rats: The Impact of Sex and Glycine Transporter Type 1 (GlyT1) Inhibitor

Adverse early life experiences are associated with an enhanced risk for mental and physical health problems, including substance abuse. Despite clinical evidence, the mechanisms underlying these relationships are not fully understood. Maternal separation (MS) is a commonly used animal model of early...

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Bibliographic Details
Main Authors: Joanna Filarowska-Jurko, Lukasz Komsta, Irena Smaga, Paulina Surowka, Marta Marszalek-Grabska, Pawel Grochecki, Dorota Nizio, Malgorzata Filip, Jolanta H. Kotlinska
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
maternal separation
male/female
ethanol drinking
reversal learning
NMDA receptor subunits
GlyT1 inhibitor
Online Access:https://www.mdpi.com/1422-0067/23/10/5350

Internet

https://www.mdpi.com/1422-0067/23/10/5350

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