Pharmacokinetic and Pharmacodynamic Rationale for Extending VEGF Inhibition Increasing Intravitreal Aflibercept Dose
Background: The effects of various dosages and treatment regimens on intravitreal aflibercept concentrations and the proportion of free vascular endothelial growth factor (VEGF) to total VEGF were evaluated using a drug and disease assessment model. The 8 mg dosage received specific attention. Metho...
| Główni autorzy: | , , , |
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| Format: | Artykuł |
| Język: | English |
| Wydane: |
MDPI AG
2023-05-01
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| Seria: | Pharmaceutics |
| Hasła przedmiotowe: | |
| Dostęp online: | https://www.mdpi.com/1999-4923/15/5/1416 |