In situ profiling reveals metabolic alterations in the tumor microenvironment of ovarian cancer after chemotherapy

In situ profiling reveals metabolic alterations in the tumor microenvironment of ovarian cancer after chemotherapy

Abstract In this study, we investigated the metabolic alterations associated with clinical response to chemotherapy in patients with ovarian cancer. Pre- and post-neoadjuvant chemotherapy (NACT) tissues from patients with high-grade serous ovarian cancer (HGSC) who had poor response (PR) or excellen...

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Bibliographic Details
Main Authors: Sara Corvigno, Sunil Badal, Meredith L. Spradlin, Michael Keating, Igor Pereira, Elaine Stur, Emine Bayraktar, Katherine I. Foster, Nicholas W. Bateman, Waleed Barakat, Kathleen M. Darcy, Thomas P. Conrads, G. Larry Maxwell, Philip L. Lorenzi, Susan K. Lutgendorf, Yunfei Wen, Li Zhao, Premal H. Thaker, Michael J. Goodheart, Jinsong Liu, Nicole Fleming, Sanghoon Lee, Livia S. Eberlin, Anil K. Sood
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-023-00454-0

Internet

https://doi.org/10.1038/s41698-023-00454-0

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