High-resolution array copy number analyses for detection of deletion, gain, amplification and copy-neutral LOH in primary neuroblastoma tumors: Four cases of homozygous deletions of the CDKN2A gene

<p>Abstract</p> <p>Background</p> <p>Neuroblastoma is a very heterogeneous pediatric tumor of the sympathetic nervous system showing clinically significant patterns of genetic alterations. Favorable tumors usually have near-triploid karyotypes with few structural rearra...

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Bibliographic Details
Main Authors: Kogner Per, Abrahamsson Jonas, Sjöberg Rose-Marie, Enerbäck Charlotta, Olsson Linda, Erichsen Jennie, Carén Helena, Martinsson Tommy
Format: Article
Language:English
Published: BMC 2008-07-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/9/353