Exploring a Nuclear-Selective Radioisotope Delivery System for Efficient Targeted Alpha Therapy

Exploring a Nuclear-Selective Radioisotope Delivery System for Efficient Targeted Alpha Therapy

Targeted alpha therapy (TAT) has garnered significant interest as an innovative cancer therapy. Owing to their high energy and short range, achieving selective α-particle accumulation in target tumor cells is crucial for obtaining high potency without adverse effects. To meet this demand, we fabrica...

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Bibliographic Details
Main Authors: Yuki Iizuka, Yoshiyuki Manabe, Kazuhiro Ooe, Atsushi Toyoshima, Xiaojie Yin, Hiromitsu Haba, Kazuya Kabayama, Koichi Fukase
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
targeted alpha therapy (TAT)
drug delivery system (DDS)
radiolabeled antibody
α-ray
imaging
nuclear localization signal (NLS)
Online Access:https://www.mdpi.com/1422-0067/24/11/9593

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https://www.mdpi.com/1422-0067/24/11/9593

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