Accurate prediction of DNA N4-methylcytosine sites via boost-learning various types of sequence features

Abstract Background DNA N4-methylcytosine (4mC) is a critical epigenetic modification and has various roles in the restriction-modification system. Due to the high cost of experimental laboratory detection, computational methods using sequence characteristics and machine learning algorithms have bee...

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Bibliographic Details
Main Authors: Zhixun Zhao, Xiaocai Zhang, Fang Chen, Liang Fang, Jinyan Li
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-020-07033-8