Accelerated Development of AAV Purification Process Using a High-Throughput and Automated Crossflow System

Accelerated Development of AAV Purification Process Using a High-Throughput and Automated Crossflow System

Adeno-associated viruses (AAV) are currently predominant viral transfer tools for gene therapy, and efforts are being made to design faster and more efficient methods and technologies for their manufacturing. The early selection of high-performing filters is essential for developing an ultrafiltrati...

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Bibliographic Details
Main Authors: Sónia Mendes, Tiago Q. Faria, André Nascimento, Marc Noverraz, Franziska Bollmann, Piergiuseppe Nestola, António Roldão, Cristina Peixoto, Ricardo J. S. Silva
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Separations
Subjects:
adeno-associated virus
downstream processing
gene therapy
process development
tangential flow filtration
Online Access:https://www.mdpi.com/2297-8739/11/3/73

Internet

https://www.mdpi.com/2297-8739/11/3/73

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