Longitudinal changes in 18F-Flutemetamol amyloid load in cognitively intact APOE4 carriers versus noncarriers: Methodological considerations

Longitudinal changes in 18F-Flutemetamol amyloid load in cognitively intact APOE4 carriers versus noncarriers: Methodological considerations

Purpose: Measuring longitudinal changes in amyloid load in the asymptomatic stage of Alzheimer’s disease is of high relevance for clinical research and progress towards more efficacious, timely treatments. Apolipoprotein E ε4 (APOE4) has a well-established effect on the rate of amyloid accumulation....

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Bibliographic Details
Main Authors: Emma S. Luckett, Jolien Schaeverbeke, Steffi De Meyer, Katarzyna Adamczuk, Koen Van Laere, Patrick Dupont, Rik Vandenberghe
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:NeuroImage: Clinical
Subjects:
Alzheimer’s disease
APOE4
Longitudinal study
Amyloid-PET
18F-Flutemetamol
Reference region
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158223000104

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http://www.sciencedirect.com/science/article/pii/S2213158223000104

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