Response to immune checkpoint blockade improved in pre-clinical model of breast cancer after bariatric surgery

Response to immune checkpoint blockade improved in pre-clinical model of breast cancer after bariatric surgery

Bariatric surgery is a sustainable weight loss approach, including vertical sleeve gastrectomy (VSG). Obesity exacerbates tumor growth, while diet-induced weight loss impairs progression. It remains unknown how bariatric surgery-induced weight loss impacts cancer progression or alters response to th...

Full description

Bibliographic Details
Main Authors: Laura M Sipe, Mehdi Chaib, Emily B Korba, Heejoon Jo, Mary Camille Lovely, Brittany R Counts, Ubaid Tanveer, Jeremiah R Holt, Jared C Clements, Neena A John, Deidre Daria, Tony N Marion, Margaret S Bohm, Radhika Sekhri, Ajeeth K Pingili, Bin Teng, James A Carson, D Neil Hayes, Matthew J Davis, Katherine L Cook, Joseph F Pierre, Liza Makowski
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-07-01
Series:eLife
Subjects:
immunotherapy
obesity
sleeve gastrectomy
breast cancer
metabolic surgery
PD-L1
Online Access:https://elifesciences.org/articles/79143

Internet

https://elifesciences.org/articles/79143

Similar Items