Functions of CD1d-Restricted Invariant Natural Killer T Cells in Antimicrobial Immunity and Potential Applications for Infection Control

Functions of CD1d-Restricted Invariant Natural Killer T Cells in Antimicrobial Immunity and Potential Applications for Infection Control

CD1d-restricted invariant natural killer T (iNKT) cells are innate-type lymphocytes that express a T-cell receptor (TCR) containing an invariant α chain encoded by the Vα14 gene in mice and Vα24 gene in humans. These iNKT cells recognize endogenous, microbial, and synthetic glycolipid antigens prese...

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Bibliographic Details
Main Authors: Yuki Kinjo, Shogo Takatsuka, Naoki Kitano, Shun Kawakubo, Masahiro Abe, Keigo Ueno, Yoshitsugu Miyazaki
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
invariant natural killer T cell
CD1d
glycolipid
adjuvant activity
microbial infection
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01266/full

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https://www.frontiersin.org/article/10.3389/fimmu.2018.01266/full

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