Mechanical Load and Piezo1 Channel Regulated Myosin II Activity in Mouse Lenses

Mechanical Load and Piezo1 Channel Regulated Myosin II Activity in Mouse Lenses

The cytoarchitecture and tensile characteristics of ocular lenses play a crucial role in maintaining their transparency and deformability, respectively, which are properties required for the light focusing function of ocular lens. Calcium-dependent myosin-II-regulated contractile characteristics and...

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Bibliographic Details
Main Authors: Ariana Allen, Rupalatha Maddala, Camelia Eldawy, Ponugoti Vasantha Rao
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
lens
piezo channel
stiffness
myosin II
calpain
mechanotransduction
Online Access:https://www.mdpi.com/1422-0067/23/9/4710

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https://www.mdpi.com/1422-0067/23/9/4710

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