Altered cardiac electrophysiology and SUDEP in a model of Dravet syndrome.

Altered cardiac electrophysiology and SUDEP in a model of Dravet syndrome.

OBJECTIVE:Dravet syndrome is a severe form of intractable pediatric epilepsy with a high incidence of SUDEP: Sudden Unexpected Death in epilepsy. Cardiac arrhythmias are a proposed cause for some cases of SUDEP, yet the susceptibility and potential mechanism of arrhythmogenesis in Dravet syndrome re...

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Bibliographic Details
Main Authors: David S Auerbach, Julie Jones, Brittany C Clawson, James Offord, Guy M Lenk, Ikuo Ogiwara, Kazuhiro Yamakawa, Miriam H Meisler, Jack M Parent, Lori L Isom
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3796479?pdf=render

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http://europepmc.org/articles/PMC3796479?pdf=render

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