Dynamic changes in immune cells in humanized liver metastasis and subcutaneous xenograft mouse models
Abstract Preclinical drug efficacy and tumor microenvironment (TME) investigations often utilize humanized xenograft mouse models, yet these models typically fall short in replicating the intricate TME. We developed a humanized liver metastasis (LM) model by transplanting human peripheral blood mono...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-09-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-024-69988-y |