Comparison of DNA methylation profiles from saliva in Coeliac disease and non-coeliac disease individuals

Comparison of DNA methylation profiles from saliva in Coeliac disease and non-coeliac disease individuals

Abstract Background Coeliac disease (CD) is a autoimmune disease characterised by mucosal inflammation in the small intestine in response to dietary gluten. Genetic factors play a key role with CD individuals carrying either the HLA-DQ2 or HLA-DQ8 haplotype, however these haplotypes are present in h...

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Bibliographic Details
Main Authors: Nerissa L. Hearn, Christine L. Chiu, Joanne M. Lind
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Medical Genomics
Subjects:
Coeliac disease
DNA methylation
Gluten-free diet
Saliva
Online Access:https://doi.org/10.1186/s12920-020-0670-9

Internet

https://doi.org/10.1186/s12920-020-0670-9

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