Pathogenic Genome Signatures That Damage Motor Neurons in Amyotrophic Lateral Sclerosis

Pathogenic Genome Signatures That Damage Motor Neurons in Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is the most frequent motor neuron disease and a neurodegenerative disorder, affecting the upper and/or lower motor neurons. Notably, it invariably leads to death within a few years of onset. Although most ALS cases are sporadic, familial amyotrophic lateral sclero...

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Bibliographic Details
Main Authors: Ali Yousefian-Jazi, YunHee Seol, Jieun Kim, Hannah L. Ryu, Junghee Lee, Hoon Ryu
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cells
Subjects:
amyotrophic lateral sclerosis
motor neuron
genome signature
cell damage
neurodegeneration
Online Access:https://www.mdpi.com/2073-4409/9/12/2687

Internet

https://www.mdpi.com/2073-4409/9/12/2687

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