Decoding of the ubiquitin code for clearance of colliding ribosomes by the RQT complex

The colliding ribosomes are ubiquitinated by the sensor protein Hel2, leading to noncanonical subunit dissociation by the ribosome associated quality control trigger (RQT) complex. Here the authors reveal the decoding mechanism of the ribosome ubiquitin code by the RQT complex.

Bibliographic Details
Main Authors: Yoshitaka Matsuo, Takayuki Uchihashi, Toshifumi Inada
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-35608-4