Decoding of the ubiquitin code for clearance of colliding ribosomes by the RQT complex
The colliding ribosomes are ubiquitinated by the sensor protein Hel2, leading to noncanonical subunit dissociation by the ribosome associated quality control trigger (RQT) complex. Here the authors reveal the decoding mechanism of the ribosome ubiquitin code by the RQT complex.
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-01-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-35608-4 |
| _version_ | 1797952417519632384 |
|---|---|
| author | Yoshitaka Matsuo Takayuki Uchihashi Toshifumi Inada |
| author_facet | Yoshitaka Matsuo Takayuki Uchihashi Toshifumi Inada |
| author_sort | Yoshitaka Matsuo |
| collection | DOAJ |
| description | The colliding ribosomes are ubiquitinated by the sensor protein Hel2, leading to noncanonical subunit dissociation by the ribosome associated quality control trigger (RQT) complex. Here the authors reveal the decoding mechanism of the ribosome ubiquitin code by the RQT complex. |
| first_indexed | 2024-04-10T22:47:05Z |
| format | Article |
| id | doaj.art-6cec7fce5f374befb8da3f894d3a96fd |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-10T22:47:05Z |
| publishDate | 2023-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-6cec7fce5f374befb8da3f894d3a96fd2023-01-15T12:16:16ZengNature PortfolioNature Communications2041-17232023-01-0114111210.1038/s41467-022-35608-4Decoding of the ubiquitin code for clearance of colliding ribosomes by the RQT complexYoshitaka Matsuo0Takayuki Uchihashi1Toshifumi Inada2Division of RNA and Gene regulation, Institute of Medical Science, The University of TokyoDepartment of Physics, Nagoya UniversityDivision of RNA and Gene regulation, Institute of Medical Science, The University of TokyoThe colliding ribosomes are ubiquitinated by the sensor protein Hel2, leading to noncanonical subunit dissociation by the ribosome associated quality control trigger (RQT) complex. Here the authors reveal the decoding mechanism of the ribosome ubiquitin code by the RQT complex.https://doi.org/10.1038/s41467-022-35608-4 |
| spellingShingle | Yoshitaka Matsuo Takayuki Uchihashi Toshifumi Inada Decoding of the ubiquitin code for clearance of colliding ribosomes by the RQT complex Nature Communications |
| title | Decoding of the ubiquitin code for clearance of colliding ribosomes by the RQT complex |
| title_full | Decoding of the ubiquitin code for clearance of colliding ribosomes by the RQT complex |
| title_fullStr | Decoding of the ubiquitin code for clearance of colliding ribosomes by the RQT complex |
| title_full_unstemmed | Decoding of the ubiquitin code for clearance of colliding ribosomes by the RQT complex |
| title_short | Decoding of the ubiquitin code for clearance of colliding ribosomes by the RQT complex |
| title_sort | decoding of the ubiquitin code for clearance of colliding ribosomes by the rqt complex |
| url | https://doi.org/10.1038/s41467-022-35608-4 |
| work_keys_str_mv | AT yoshitakamatsuo decodingoftheubiquitincodeforclearanceofcollidingribosomesbytherqtcomplex AT takayukiuchihashi decodingoftheubiquitincodeforclearanceofcollidingribosomesbytherqtcomplex AT toshifumiinada decodingoftheubiquitincodeforclearanceofcollidingribosomesbytherqtcomplex |