Removal of natural anti-αGal antibodies elicits protective immunity against Gram-negative bacterial infections

Removal of natural anti-αGal antibodies elicits protective immunity against Gram-negative bacterial infections

Antibody-dependent enhancement (ADE) of bacterial infections occurs when blocking or inhibitory antibodies facilitate the infectivity of pathogens. In humans, antibodies involved in ADE of bacterial infections may include those naturally produced against Galα1-3Galβ1-4GlcNAcβ (αGal). Here, we invest...

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Bibliographic Details
Main Authors: Sara Olivera-Ardid, Daniel Bello-Gil, Magdiel Perez-Cruz, Cristina Costa, Mariana Camoez, M. Angeles Dominguez, Yara Ferrero-Alves, Jose Miguel Vaquero, Nailya Khasbiullina, Nadezhda V. Shilova, Nicolai V. Bovin, Rafael Mañez
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Immunology
Subjects:
antibody-dependent-enhancement of infection
anti-αGal antibodies
removal of antibodies
Gram-negative bacteria
protective immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1232924/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1232924/full

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