A meta-analytic evaluation of the correlation between event-free survival and overall survival in randomized controlled trials of newly diagnosed Ewing sarcoma

A meta-analytic evaluation of the correlation between event-free survival and overall survival in randomized controlled trials of newly diagnosed Ewing sarcoma

Abstract Background In randomized controlled trials (RCTs) of adjuvant treatment for malignant tumors, event-free survival (EFS) is considered the most acceptable surrogate for overall survival (OS). However, even though EFS has repeatedly been selected as a primary endpoint in RCTs of Ewing sarcoma...

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Bibliographic Details
Main Authors: Kazuhiro Tanaka, Masanori Kawano, Tatsuya Iwasaki, Ichiro Itonaga, Hiroshi Tsumura
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Cancer
Subjects:
Ewing sarcoma
Randomized controlled trial
Chemotherapy
Endpoint
Surrogacy
Overall survival
Online Access:http://link.springer.com/article/10.1186/s12885-020-06871-9

Internet

http://link.springer.com/article/10.1186/s12885-020-06871-9

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