AAACH is a conserved motif in a cis-acting replication element that is artificially inserted into Senecavirus A genome

AAACH is a conserved motif in a cis-acting replication element that is artificially inserted into Senecavirus A genome

Cis-acting replication element (cre) is required for generating a diuridylylated VPg that acts as a protein primer to initiate the synthesis of picornaviral genome or antigenome. The cre is a stem–loop structure, dependent of different picornaviruses, located in different genomic regions. The AAACA...

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Bibliographic Details
Main Authors: Mengyao Wang, Di Zhao, Jing Li, Lijie Zhu, Xiaoxiao Duan, Youming Zhang, Yan Li, Fuxiao Liu
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Virus Research
Subjects:
Senecavirus A
Cis-acting replication element
AAACA motif
Artificial cre
Virus rescue
Point mutation
Online Access:http://www.sciencedirect.com/science/article/pii/S0168170223002319

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http://www.sciencedirect.com/science/article/pii/S0168170223002319

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