Gamma-Aminobutyric Acid (GABA) Promotes Growth in Zebrafish Larvae by Inducing IGF-1 Expression via GABA<sub>A</sub> and GABA<sub>B</sub> Receptors

Gamma-Aminobutyric Acid (GABA) Promotes Growth in Zebrafish Larvae by Inducing IGF-1 Expression via GABA<sub>A</sub> and GABA<sub>B</sub> Receptors

Insulin-like growth factor-1 (IGF-1) primarily increases the release of gamma-aminobutyric acid (GABA) in neurons; moreover, it is responsible for the promotion of longitudinal growth in children and adolescents. Therefore, in this study, we investigated whether exogenous GABA supplementation activa...

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Bibliographic Details
Main Authors: Athapaththu Mudiyanselage Gihan Kavinda Athapaththu, Ilandarage Menu Neelaka Molagoda, Rajapaksha Gedara Prasad Tharanga Jayasooriya, Yung Hyun Choi, You-Jin Jeon, Joung-Hyun Park, Bae-Jin Lee, Gi-Young Kim
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
GABA
IGF-1
GABA receptors
growth performance
Online Access:https://www.mdpi.com/1422-0067/22/20/11254

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https://www.mdpi.com/1422-0067/22/20/11254

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