The boosting effects of melatonin on the expression of related genes to oocyte maturation and antioxidant pathways: a polycystic ovary syndrome- mouse model

Abstract Background Melatonin, as a free radical scavenger exhibiting genomic actions, regulates the antioxidant genes expression and apoptosis mechanisms. In polycystic ovary syndrome (PCOS) patients, an imbalance between free radicals and antioxidants in follicular fluid leads to oxidative stress,...

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Bibliographic Details
Main Authors: Fatemeh Nikmard, Elham Hosseini, Mehrdad Bakhtiyari, Mahnaz Ashrafi, Fardin Amidi, Reza Aflatoonian
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Journal of Ovarian Research
Subjects:
Online Access:https://doi.org/10.1186/s13048-022-00946-w