Improved mass spectrometry assay for plasma hepcidin: detection and characterization of a novel hepcidin isoform.

Improved mass spectrometry assay for plasma hepcidin: detection and characterization of a novel hepcidin isoform.

Mass spectrometry (MS)-based assays for the quantification of the iron regulatory hormone hepcidin are pivotal to discriminate between the bioactive 25-amino acid form that can effectively block the sole iron transporter ferroportin and other naturally occurring smaller isoforms without a known role...

Full description

Bibliographic Details
Main Authors: Coby M M Laarakkers, Erwin T Wiegerinck, Siem Klaver, Maria Kolodziejczyk, Hendrik Gille, Andreas M Hohlbaum, Harold Tjalsma, Dorine W Swinkels
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3790851?pdf=render

Internet

http://europepmc.org/articles/PMC3790851?pdf=render

Similar Items