Prion propagation in vitro: are we there yet?

<p>Prion diseases are caused by proteinaceous pathogens termed prions. Although the details of the mechanism of prion propagation are not fully understood, conformational conversion of cellular prion protein (PrP<sup>C</sup>) to misfolded, disease-associated scrapie prion protein (...

Full description

Bibliographic Details
Main Author: Chongsuk Ryou, Charles E. Mays
Format: Article
Language:English
Published: Ivyspring International Publisher 2008-01-01
Series:International Journal of Medical Sciences
Online Access:http://www.medsci.org/v05p0347.htm