Prion propagation in vitro: are we there yet?
<p>Prion diseases are caused by proteinaceous pathogens termed prions. Although the details of the mechanism of prion propagation are not fully understood, conformational conversion of cellular prion protein (PrP<sup>C</sup>) to misfolded, disease-associated scrapie prion protein (...
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Format: | Article |
Language: | English |
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Ivyspring International Publisher
2008-01-01
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Series: | International Journal of Medical Sciences |
Online Access: | http://www.medsci.org/v05p0347.htm |