Ginsenoside Rg1 Exerts Anti-inflammatory Effects via G Protein-Coupled Estrogen Receptor in Lipopolysaccharide-Induced Microglia Activation

Ginsenoside Rg1 Exerts Anti-inflammatory Effects via G Protein-Coupled Estrogen Receptor in Lipopolysaccharide-Induced Microglia Activation

Neuroinflammation plays a pivotal role in the pathogenesis of Parkinson’s disease. Ginsenoside Rg1, the most active ingredient of ginseng, has been reported to exert neuroprotective effects via estrogen and glucocorticoid receptors. The present study evaluated the involvement of the G protein-couple...

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Bibliographic Details
Main Authors: Xian-Qi Gao, Zhong-Rui Du, Liang-Jie Yuan, Wen-Di Zhang, Lei Chen, Ji-Jun Teng, Man-Sau Wong, Jun-Xia Xie, Wen-Fang Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Neuroscience
Subjects:
ginsenoside Rg1
G protein-coupled estrogen receptor
lipopolysaccharide
neuroinflammation
microglial cells
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.01168/full

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https://www.frontiersin.org/article/10.3389/fnins.2019.01168/full

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