Nephroprotective effects of the soluble guanylyl cyclase stimulator, riociguat in doxorubicin-induced acute kidney injury in rats

This study aimed to investigate the potential protective effects of riociguat, a soluble guanylyl cyclase (sGC) stimulator, on kidney function and structure in rats with acute kidney injury (AKI) induced by the chemotherapeutic drug doxorubicin (DX). Rats were subjected to a single intraperitoneal i...

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Bibliographic Details
Main Authors: Raya Al-Maskari, Aly M. Abdelrahman, Haytham Ali, Priyadarsini Manoj, Yousuf Al Suleimani
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Toxicology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750024001835