Durable cross-protective neutralizing antibody responses elicited by lipid nanoparticle-formulated SARS-CoV-2 mRNA vaccines

Abstract The advent of SARS-CoV-2 variants with defined mutations that augment pathogenicity and/or increase immune evasiveness continues to stimulate global efforts to improve vaccine formulation and efficacy. The extraordinary advantages of lipid nanoparticles (LNPs), including versatile design, s...

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Bibliographic Details
Main Authors: Ki Hyun Bae, Bhuvaneshwari Shunmuganathan, Li Zhang, Andrew Lim, Rashi Gupta, Yanming Wang, Boon Lin Chua, Yang Wang, Yue Gu, Xinlei Qian, Isabelle Siang Ling Tan, Kiren Purushotorman, Paul A. MacAry, Kevin P. White, Yi Yan Yang
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-024-00835-x