Standardized IMGT® Nomenclature of Salmonidae IGH Genes, the Paradigm of Atlantic Salmon and Rainbow Trout: From Genomics to Repertoires

In teleost fish as in mammals, humoral adaptive immunity is based on B lymphocytes expressing highly diverse immunoglobulins (IG). During B cell differentiation, IG loci are subjected to genomic rearrangements of V, D, and J genes, producing a unique antigen receptor expressed on the surface of each...

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Main Authors: Susana Magadan, Aleksei Krasnov, Saida Hadi-Saljoqi, Sergey Afanasyev, Stanislas Mondot, Delphine Lallias, Rosario Castro, Irene Salinas, Oriol Sunyer, John Hansen, Ben F. Koop, Marie-Paule Lefranc, Pierre Boudinot
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02541/full