Estrogen deficiency induces bone loss through the gut microbiota

Estrogen deficiency induces bone loss through the gut microbiota

Postmenopausal osteoporosis is a common bone metabolic disease, and gut microbiota (GM) imbalance plays an important role in the development of metabolic bone disease. Here, we show that ovariectomized mice had high levels of lipopolysaccharide in serum and gut microbiota dysbiosis through increases...

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Bibliographic Details
Main Authors: Zhiyuan Guan, Zheng Xuanqi, Junxiong Zhu, Wanqiong Yuan, Jialin Jia, Chenggui Zhang, Tiantong Sun, Huijie Leng, Changtao Jiang, Yingsheng Xu, Chunli Song
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Pharmacological Research
Subjects:
Osteoporosis
Gut microbiota
Ovariectomy
Bone metabolism
TGR5
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661823002864

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http://www.sciencedirect.com/science/article/pii/S1043661823002864

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