Characterization of novel bacteriophage PSKP16 and its therapeutic potential against β-lactamase and biofilm producer strain of K2-Hypervirulent Klebsiella pneumoniae pneumonia infection in mice model

Characterization of novel bacteriophage PSKP16 and its therapeutic potential against β-lactamase and biofilm producer strain of K2-Hypervirulent Klebsiella pneumoniae pneumonia infection in mice model

Abstract Background Severe infections caused by β- lactamase producers, hypervirulent Klebsiella pneumoniae (BhvKp) with K2 serotype, highlight emergency need for new therapeutic strategies against this pathogen. We aimed to assess the efficacy of a novel phage, PSKP16, in the treating of pneumonia...

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Bibliographic Details
Main Authors: Sara Rahimi, Mehdi Bakht, Amir Javadi, Farshad Foroughi, Seyed Mahmoud Amin Marashi, Farhad Nikkhahi
Format: Article
Language:English
Published: BMC 2023-08-01
Series:BMC Microbiology
Subjects:
Bacteriophage
Hypervirulent
Klebsiella pneumoniae
β-lactamase
Biofilm
Mice model
Online Access:https://doi.org/10.1186/s12866-023-02979-7

Internet

https://doi.org/10.1186/s12866-023-02979-7

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