5-Fluorouracil/Coumarin and 5-Fluorouracil/Chromone Hybrids: Synthesis and Drug-Likeness Modeling

A series of 5-fluorouracil/coumarin and 5-fluorouracil/chromone hybrids were synthesized with good yields using click chemistry as the key step. The structures of these compounds and all intermediates were elucidated by spectroscopic analysis. Furthermore, pharmacokinetic and drug-like computations...

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Bibliographic Details
Main Authors: Laura Giraldo-Arroyave, Andrés F. Yepes, Wilson Cardona-Galeano
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Molbank
Subjects:
Online Access:https://www.mdpi.com/1422-8599/2024/1/M1779