A role for human mitochondrial complex II in the production of reactive oxygen species in human skin

The mitochondrial respiratory chain is a major generator of cellular oxidative stress, thought to be an underlying cause of the carcinogenic and ageing process in many tissues including skin. Previous studies of the relative contributions of the respiratory chain (RC) complexes I, II and III towards...

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Bibliographic Details
Main Authors: Alasdair Anderson, Amy Bowman, Sarah Jayne Boulton, Philip Manning, Mark A. Birch-Machin
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231714000950