Plasticity of Membrane Binding by the Central Region of α-Synuclein

Membrane binding by α-synuclein (αS), an intrinsically disordered protein whose aggregation is associated with Parkinson’s disease, is a key step in determining its biological properties under both physiological and pathological conditions. Upon membrane interaction, αS retains a partial level of st...

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Bibliographic Details
Main Authors: Carlos Navarro-Paya, Maximo Sanz-Hernandez, Alfonso De Simone
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.857217/full