Bioengineering the neurovascular niche to study the interaction of neural stem cells and endothelial cells

The ability of mammalian neural stem cells (NSCs) to self-renew and differentiate throughout adulthood has made them ideal to study neurogenesis and attractive candidates for neurodegenerative disease therapies. In the adult mammalian brain, NSCs are maintained in the neurovascular niche (NVN) where...

Full description

Bibliographic Details
Main Authors: Max A. Winkelman, Abigail N. Koppes, Ryan A. Koppes, Guohao Dai
Format: Article
Language:English
Published: AIP Publishing LLC 2021-03-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/5.0027211