Closed-loop brain stimulation augments fear extinction in male rats

Abstract Dysregulated fear reactions can result from maladaptive processing of trauma-related memories. In post-traumatic stress disorder (PTSD) and other psychiatric disorders, dysfunctional extinction learning prevents discretization of trauma-related memory engrams and generalizes fear responses....

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Bibliographic Details
Main Authors: Rodrigo Ordoñez Sierra, Lizeth Katherine Pedraza, Lívia Barcsai, Andrea Pejin, Qun Li, Gábor Kozák, Yuichi Takeuchi, Anett J. Nagy, Magor L. Lőrincz, Orrin Devinsky, György Buzsáki, Antal Berényi
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39546-7