Mechanism Exploration of Arylpiperazine Derivatives Targeting the 5-HT2A Receptor by In Silico Methods

As a G-protein coupled receptor, the 5-hydroxytryptamine 2A (5-HT2A) receptor is known for its critical role in the cognitive, behavioural and physiological functions, and thus is a primary molecular target to treat psychiatric diseases, including especially depression. With purpose to explore the s...

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Bibliographic Details
Main Authors: Feng Lin, Feng Li, Chao Wang, Jinghui Wang, Yinfeng Yang, Ling Yang, Yan Li
Format: Article
Language:English
Published: MDPI AG 2017-06-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/22/7/1064