Dopamine neurons drive fear extinction learning by signaling the omission of expected aversive outcomes

Extinction of fear responses is critical for adaptive behavior and deficits in this form of safety learning are hallmark of anxiety disorders. However, the neuronal mechanisms that initiate extinction learning are largely unknown. Here we show, using single-unit electrophysiology and cell-type speci...

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Bibliographic Details
Main Authors: Ximena I Salinas-Hernández, Pascal Vogel, Sebastian Betz, Raffael Kalisch, Torfi Sigurdsson, Sevil Duvarci
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-11-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/38818