Hyperforin Ameliorates Imiquimod-Induced Psoriasis-Like Murine Skin Inflammation by Modulating IL-17A–Producing γδ T Cells

Hyperforin Ameliorates Imiquimod-Induced Psoriasis-Like Murine Skin Inflammation by Modulating IL-17A–Producing γδ T Cells

Hyperforin is a major active constituent of Hypericum perforatum L. extract, which is widely used for the treatment of depressive disorders. Recent studies have reported that hyperforin reduced inflammation in stroke and suppressed proliferation and differentiation in keratinocytes. Psoriasis is a c...

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Bibliographic Details
Main Authors: Song Zhang, Jia Zhang, Juanjuan Yu, Xiaolu Chen, Fangyuan Zhang, Wei Wei, Lingyun Zhang, Wenmao Chen, Nengxing Lin, Yan Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
IL-17A
psoriasis
hyperforin
γδT cells
Stat3
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.635076/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.635076/full

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