Antinociceptive effects of dexmedetomidine via spinal substance P and CGRP

Antinociceptive effects of dexmedetomidine via spinal substance P and CGRP

The aim of this study was to examine the role played by substance P and calcitonin gene-related peptide (CGRP) within the dorsal horn of the spinal cord in engagement of antinociception evoked by dexmedetomidine (DEX). Paw withdrawal threshold (PWT) to mechanical stimulation was determined after chr...

Full description

Bibliographic Details
Main Authors: Li Ruiqin, Qi Feng, Zhang Junlong, Ji Yong, Zhang Dengxin, Shen Zhiyun, Lei Weifu
Format: Article
Language:English
Published: De Gruyter 2015-01-01
Series:Translational Neuroscience
Subjects:
dexmedetomidine
pain modulation
substance p
calcitonin gene-related peptide (cgrp)
dorsal horn
Online Access:https://doi.org/10.1515/tnsci-2015-0028

Internet

https://doi.org/10.1515/tnsci-2015-0028

Similar Items