Picroside II Isolated from <i>Pseudolysimachion rotundum var. subintegrum</i> Inhibits Glucocorticoid Refractory Serum Amyloid A (SAA) Expression and SAA-induced IL-33 Secretion

Picroside II Isolated from <i>Pseudolysimachion rotundum var. subintegrum</i> Inhibits Glucocorticoid Refractory Serum Amyloid A (SAA) Expression and SAA-induced IL-33 Secretion

Chronic obstructive pulmonary disease (COPD) is a major inflammatory lung disease characterized by irreversible and progressive airflow obstruction. Although corticosteroids are often used to reduce inflammation, steroid therapies are insufficient in patients with refractory COPD. Both serum amyloid...

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Bibliographic Details
Main Authors: Kiram Lee, Jin Choi, Bo Kyong Choi, Young-Mi Gu, Hyung Won Ryu, Sei-Ryang Oh, Hyun-Jun Lee
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Molecules
Subjects:
Picroside II
<i>Pseudolysimachion rotundum</i> var. subintegrum
serum amyloid A
IL-33
steroid-resistance
airway epithelial cells
Online Access:https://www.mdpi.com/1420-3049/24/10/2020

Internet

https://www.mdpi.com/1420-3049/24/10/2020

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