c-Cbl: An Important Regulator and a Target in Angiogenesis and Tumorigenesis
Casitas B lineage lymphoma (c-Cbl) is a multifunctional protein with a ubiquitin E3 ligase activity capable of degrading diverse sets of proteins. Although previous work had focused mainly on c-Cbl mutations in humans with hematological malignancies, recent emerging evidence suggests a critical role...
Main Authors: | Chimera L. Lyle, Mostafa Belghasem, Vipul C. Chitalia |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-05-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/8/5/498 |
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