Co-Expression of the B-Cell Key Transcription Factors Blimp-1 and IRF4 Identifies Plasma Cells in the Pig

Co-Expression of the B-Cell Key Transcription Factors Blimp-1 and IRF4 Identifies Plasma Cells in the Pig

Antibody-secreting plasma cells (PCs) have remained largely uncharacterized for years in the field of porcine immunology. For an in-depth study of porcine PCs, we identified cross-reactive antibodies against three key transcription factors: PR domain zinc finger protein-1 (Blimp-1), interferon regul...

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Bibliographic Details
Main Authors: Sonia Villanueva-Hernández, Mahsa Adib Razavi, Katinka A. van Dongen, Maria Stadler, Karelle de Luca, Niklas Beyersdorf, Armin Saalmüller, Wilhelm Gerner, Kerstin H. Mair
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Immunology
Subjects:
pig
plasma cells
BLIMP-1
IRF4
immunoglobulin classes
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.854257/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.854257/full

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