Cochlear implantation impairs intracochlear microcirculation and counteracts iNOS induction in guinea pigs

Cochlear implantation impairs intracochlear microcirculation and counteracts iNOS induction in guinea pigs

IntroductionPreservation of residual hearing remains a great challenge during cochlear implantation. Cochlear implant (CI) electrode array insertion induces changes in the microvasculature as well as nitric oxide (NO)-dependent vessel dysfunction which have been identified as possible mediators of r...

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Bibliographic Details
Main Authors: Benjamin Philipp Ernst, Ulf-Rüdiger Heinrich, Mathias Fries, Regina Meuser, Tobias Rader, Jonas Eckrich, Roland H. Stauber, Sebastian Strieth
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
nitric oxide
cochlea implantation
hearing preservation
cochlear microcirculation
microvascular permeability
iNOS
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2023.1189980/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2023.1189980/full

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