CD39/CD73/A2AR pathway and cancer immunotherapy
Abstract Cancer development is closely associated with immunosuppressive tumor microenvironment (TME) that attenuates antitumor immune responses and promotes tumor cell immunologic escape. The sequential conversion of extracellular ATP into adenosine by two important cell-surface ectonucleosidases C...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-03-01
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Series: | Molecular Cancer |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12943-023-01733-x |